Arhgef7 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comArhgef7 ELISA Kit for Rat(Rattus norvegicus)

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Arhgef7 (Gene name),

Rho guanine nucleotide exchange factor 7 (Protein name ), ARHG7_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Arhgef7(Pak3bp;Pixb);

Protein name:

Rho guanine nucleotide exchange factor 7;

Alternative:

PAK-interacting exchange factor beta;Beta-Pix;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with SCRIB; interaction is direct and may play a role in regulation of apoptosis (By similarity). Interacts with PAK kinases through the SH3 domain. Interacts with GIT1 and probably TGFB1I1. Interacts with ITCH. Interacts with FRMPD4 (via N-terminus). Interacts with CaMK1.

Function:

Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. May function as a positive regulator of apoptosis. May function in cell migration. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

646

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

646:

VQELRQDNKK | MKKSLEEEQR | ARKDLEKLVR | KVLKNMNDPA | WDETNL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

10116.ENSRNOP00000043761

Pfam:

PF00169

UniGene:

Rn.146763

KEGG:

rno:114559

String:

O55043

SMR:

O55043

Uniprot:

O55043

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ELISA Kit for Rat Rho guanine nucleotide exchange factor 7

Cat.:

E14325r

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96T

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ELISA Kit for Rat Rho guanine nucleotide exchange factor 7

Cat.:

E14325h

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96T

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ELISA Kit for Rat Rho guanine nucleotide exchange factor 7

Cat.:

E14325m

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96T

CLIA Kit for Rat Rho guanine nucleotide exchange factor 7

Cat.:

U14325m

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96T

CLIA Kit for Rat Rho guanine nucleotide exchange factor 7

Cat.:

U14325r

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MSDS:

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Packing:

96T

CLIA Kit for Rat Rho guanine nucleotide exchange factor 7

Cat.:

U14325h

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96T

Polyclonal Antibody for Rat Rho guanine nucleotide exchange factor 7

Cat.:

P14325Rb-r

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40ug/0.2ml

Polyclonal Antibody for Rat Rho guanine nucleotide exchange factor 7

Cat.:

P14325Rb-m

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40ug/0.2ml

Polyclonal Antibody for Rat Rho guanine nucleotide exchange factor 7

Cat.:

P14325Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Rho guanine nucleotide exchange factor 7

Protein for Rat Rho guanine nucleotide exchange factor 7

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"PAK kinases are directly coupled to the PIX family of nucleotide exchange factors."
Manser E. , Loo T.-H. , Koh C.-G. , Zhao Z.-S. , Chen X.-Q. , Tan L. , Tan I. , Leung T. , Lim L.
Mol. Cell1:183-192(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The GIT family of ADP-ribosylation factor GTPase-activating proteins. Functional diversity of GIT2 through alternative splicing."
Premont R.T. , Claing A. , Vitale N. , Perry S.J. , Lefkowitz R.J.
J. Biol. Chem.275:22373-22380(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GIT1
3.

"Cbl promotes clustering of endocytic adaptor proteins."
Jozic D. , Cardenes N. , Deribe Y.L. , Moncalian G. , Hoeller D. , Groemping Y. , Dikic I. , Rittinger K. , Bravo J.
Nat. Struct. Mol. Biol.12:972-979(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) OF 5-66
4.

"Crystal structure of the SH3 domain of betaPIX in complex with a high affinity peptide from PAK2."
Hoelz A. , Janz J.M. , Lawrie S.D. , Corwin B. , Lee A. , Sakmar T.P.
J. Mol. Biol.358:509-522(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (0.92 ANGSTROMS) OF 10-63 IN COMPLEX WITH PAK2;SUBUNIT
5.

"A novel interaction between atrophin-interacting protein 4 and beta-p21-activated kinase-interactive exchange factor is mediated by an SH3 domain."
Janz J.M. , Sakmar T.P. , Min K.C.
J. Biol. Chem.282:28893-28903(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 10-63 IN COMPLEX WITH ITCH

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